It is important to note that these classes of rejection are based on Banff classification. In both major types of humoral rejection, the glomeruli, the arteries and arterioles, capillary basement membranes and the interstitium are largely affected with loss of function being a remarkable observation. It is evident that despite there being several explanations on the mechanism of kidney allograft rejection much is still unknown about the mechanism thus the continued high prevalence of renal allograft rejection.
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